A Kambo cleansing, which is frequently referred to as a Sapo or Kambo circle, is a specific type of purge that uses skin secretions from a species of frog. The secretions are administered to trigger a psychedelic response in the individual participating in the ceremony. The ceremony originated as a folk medicine practice among indigenous populations in the Amazon. Ceremonies were led by shamans who guided others on a religious, spiritual journey. The treatment can also be given as an alternative medical treatment in the west; however, research into this type of detox is still ongoing. The ceremony usually involves burning one of the limbs before administering the secretions of the frog directly onto the burn. Proponents of the treatment claim that this type of administration can help people recover from injuries and illnesses, but research is still ongoing.